Vinpocetine is an extract of the periwinkle plant (Vinca minor), a vine-like plant commonly used as garden ground cover. Vinpocetine is derived from compound vincamine, which is naturally occurring in the seeds of the periwinkle. Vinpocetine was first isolated in 1975 by the Hungarian chemist Csaba Szantay, and mass production began in 1978 . Vinpocetine has been used worldwide ever since. Vinpocetine appears to affect ion channels (sodium, potassium, and calcium), which may contribute to the nootropic experience that makes vinpocetine a popular supplement in the United States today .
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3. Wu, S., Li, H., & Chiang, H. (2001). Vinpocetine-induced stimulation of calcium-activated potassium currents in rat pituitary GH 3 cells. Biochemical pharmacology,61(7), 877-892.
4. Sitges, M., Chiu, L. M., Guarneros, A., & Nekrassov, V. (2007). Effects of carbamazepine, phenytoin, lamotrigine, oxcarbazepine, topiramate and vinpocetine on Na+ channel-mediated release of [3 H] glutamate in hippocampal nerve endings.Neuropharmacology, 52(2), 598-605.
5. ukanova, Y. V., & Solntseva, E. (1998). Nootropic agent vinpocetine blocks delayed rectified potassium currents more strongly than high-threshold calcium currents.Neuroscience and behavioral physiology, 28(2), 116-120.
6. Kiss, B., & Karpati, E. (1996). [Mechanism of action of vinpocetine]. Acta Pharmaceutica Hungarica, 66(5), 213-224.